Hemispherectomy in the treatment of seizures: a review.
نویسنده
چکیده
The term hemispherectomy refers to the complete removal or functional disconnection of a cerebral hemisphere. The technique was initially developed over 85 years ago to treat infiltrating brain tumors but is now used exclusively for medically refractory epilepsy. Hemispherectomy surgery has progressed from an extremely morbid procedure fraught with complications to a fairly routine one performed at most pediatric epilepsy centers with relatively low risk and great efficacy. The author reviews the history and evolution of hemispherectomy surgery, the relevant pathological conditions, as well as outcomes and complications.
منابع مشابه
Milestones in the Evolution of Hemispherectomy
Surgical treatment of hemispheric epilepsy has progressively evolved from anatomical hemispherectomy to functional hemispherectomy and more recently to hemispherotomy. These developments in the surgical technique have to a large extent avoided the complications associated with large brain excisions and at the same time maintained the excellent seizure outcome associated with the surgical treatm...
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Background: The hemispherectomy is a valuable procedure in the management of seizure disorders caused by unilateral hemispheric disease. The anatomical hemispherectomy has been used for this purpose since 1938, however, it was abandoned after reports of postoperative complications caused by superficial hemosiderosis, ependymitis and obstructive hydrocephalus. So that, it has been showed modific...
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Hemimegalencephaly (HME) is a rare disorder of cortical development with overgrowth of one cerebral hemisphere. Patients have intellectual delay, hemiparesis and severe epilepsy. Drug-resistant epilepsy is often treated with a hemispherectomy. We review the literature on HME natural history and report a 26-year-old man with HME who did not undergo hemispherectomy in childhood with recurrent foc...
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Multilobar resection and hemispherectomy are surgical options available for the treatment of medically intractable seizures arising from a diffuse area of epileptogenicity that remains unilateral but extends beyond one lobe. The nature and extent of the underlying pathologic process, the patient’s neurologic status, and the results of preoperative neurophysiologic and neuroimaging studies toget...
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BACKGROUND Rasmussen encephalitis (RE) is a rare and severe brain disorder associated with unilateral hemispheric atrophy, manifesting as severe refractory epilepsy, hemiplegia, defects of motor and speech functions, and cognitive impairment. Treatment of RE, especially in adult patients, is extremely challenging. Herein, we report the case of an adult patient with RE who was treated with a fun...
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ورودعنوان ژورنال:
- Translational pediatrics
دوره 3 3 شماره
صفحات -
تاریخ انتشار 2014